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Rxn-45 bioprocessing probe
Souhrn technické specifikace
Wetted materials
Body: 316L stainless steel Window: Proprietary material, optimized for bioprocesses Process connection: PG13.5 for industry standard sensor housings, welded port connectors available Surface finish: Ra 15 with electropolish Adhesive: USP Class VI and ISO993 compatible
The Raman Rxn-45 probe capitalizes on the power of Raman in bioprocess manufacturing by measuring multiple, specific components in real-time for continuous, around-the-clock process feedback. It also meets the daunting sampling requirements of compliance, sterilization, port compatibility, and convenience. The Raman Rxn-45 probe was designed for installation in development and cGMP stainless-steel reactors and is successfully used to provide an analytical “eye” into large-scale bioprocesses.
Cell culture: glucose, lactate, amino acids, cell density, titer, and more
Fermentation: glucose, glycerol, acetate, methanol, ethanol, biomass, and more
Výhody
Measures multiple components in real-time for automated 24/7 process feedback
Provides long-term measurement stability
Offers a suitable surface finish for cGMP manufacturing
Provides compatibility with industry standard bioreactor side ports and sensor housings
Offers the flexibility of being installed in development and production reactors
Reduces sterilization and cleaning burdens with CIP/SIP standard compatibility
Ramanova spektroskopie – pokročilá technologie pro optickou analýzu
Zvyšte bezpečnost provozu, zajistěte kvalitu výrobků a optimalizujte řízení. Ramanova spektroskopie měří složení a molekulární strukturu vašich vzorků v reálném čase – z laboratoře přímo do procesu.
Raman downstream process measurement of biosimilars - Alvotech’s testing of the protein purification process during ultrafiltration/diafiltration (UF/DF)
Zvyšte bezpečnost provozu, zajistěte kvalitu výrobků a optimalizujte řízení. Ramanova spektroskopie měří složení a molekulární strukturu vašich vzorků v reálném čase – z laboratoře přímo do procesu.
Probe spectral coverage is limited by the coverage of the analyzer being used.
Maximum laser power into probehead (mW)
< 499
Sample interface
Temperature: -30 to 150 °C / -22 to 302 °F Temperature ramp: ≤ 30 °C/min ≤ 54 °F/min
Pressure
Max pressure: 13.8 barg / 200 psig
Wetted materials
Body: 316L stainless steel Window: Proprietary material, optimized for bioprocesses Process connection: PG13.5 for industry standard sensor housings, welded port connectors available Surface finish: Ra 15 with electropolish Adhesive: USP Class VI and ISO993 compatible
Endress+Hauser - your one-source Life Sciences technology partner
PU (publikace)
Anglická verze - 06/2024
New version available in English
Graphic highlighting why Endress+Hauser is trusted by the world's top biopharmaceutical manufacturers for its Life Sciences expertise and reliable inline, real-time measurement technologies like Raman spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Prioritize scalability for an efficient biopharmaceutical
product development lifecycle
PU (publikace)
Česká verze - 09/2024
New version available in English
This technical paper studies the importance of scalability as a competitive advantage in bioprocessing in the Life Science industry, and Endress+Hauser's scalable Raman systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology and Liquid Analysis portfolio (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Advanced process and product control in fermentations -
Raman spectroscopy for composition analysis in a lab
or process
PU (publikace)
Anglická verze - 03/2022
New version available in English
An overview of Raman spectroscopy analyzer systems (including the Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, and Rxn-45 probe), powered by Kaiser Raman technology, for fermentation compositional analysis in a lab or process applicable to biotechnology in the food & beverage industry.
Raman application guide for the life science industry -
Trusted composition analysis for the life sciences
PU (publikace)
Anglická verze - 04/2022
New version available in English
A guide to our Raman spectroscopy application notes for the Life Science industry (featuring the Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, Rxn-20 probe, Rxn-45 probe, Rxn-46 probe, and probe accessory optics (bIO-Optic, Raman single use optic system / SUB, immersion optic, non-contact optic).
Prioritize scalability for an efficient biopharmaceutical
product development lifecycle
PU (publikace)
Anglická verze - 06/2024
New version available in English
This technical paper studies the importance of scalability as a competitive advantage in bioprocessing in the Life Science industry, and Endress+Hauser's scalable Raman systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology and Liquid Analysis portfolio (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
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